Sensitive skin, redness, eczema, acne, hormone dependent dermatitis, barrier damaged skin, skin tingling, swelling, burning and other discomfort,photo-aging (control skin micro inflammation), pigmentation caused by inflammation and other skin problems are closely related to skin inflammation.            

After the inflammatory reaction, a wide range of complex cytokines appear in the body, which interact to form a cytokine network, in which tumor necrosis factor (TNF) plays a core role in the inflammatory reaction. TNF in general literature refers to TNFα. The proinflammatory cytokine TNFαis the earliest and most important inflammatory mediator in the process of inflammation. It can activate NFkB, produce and release a large number of inflammatory factors such as IL-1 β, IL-6, IL-8, and stimulate inflammatory chain reaction.

In addition, TNF α is one of the strongest PLA2 activators. PLA2 is the key enzyme of inflammation, which mainly causes the release of arachidonic acid, and then produces the secondary inflammatory factors PGE-2 and COX-2.

TNF α can also damage endothelial cells, regulate the expression of VEGF (endothelial growth factor), enhance the permeability of blood vessels, and make the skin produce redness. Finally, TNF α can directly or indirectly promote the expression of TRPV1, or activate TRPV1 to trigger the process of promoting pain, resulting in burning, tingling, itching and other sensory discomfort.         

It can be seen that TNF α plays an important role in the inflammatory cascade. If TNF α can effectively inhibit the expression of inflammatory factors in the process of skin inflammation, it can quickly and effectively fight against skin inflammation.

OUR SOLUTION:

Our star product SENS’FLOWER can act on the source of inflammatory response, and remarkably inhibit the expression of TNF α, and its anti-inflammatory effect is significantly better than similar anti-inflammatory products on the market. Its anti inflammatory ability in the market is on the leading level! For more product consultation, please contact us.