Trade name

Cell’intact®

Claims

Antioxidant – Anti-pollution

Studies and results-(antioxidant)

In tubo – abiotic
Protection against the oxidative attacks produced by a thermolabile free radical (ORAC study)

In vitro
Protection of the probe fluorescence against oxidation by hydrogen peroxides (DCFH study)

Ex vivo
Significant reduction of the MDA – MalonDiAldehyde- release >> protection against lipoperoxidation (MDA study)
Study of 2 tight junctions proteins, Claudins-1 and -4 expression in case of UV aggressions >> protection against proteins oxidation (immunostaining)
Study of the glyoxalase I expression, enzyme that sets off in case of an oxidative attack of the cell >> physiological level of this cell detoxification system kept (immunostaining)

Studies and results-(anti-pollution)

New ex vivo tests:
In presence of a pollutant (benzo(a)pyrene), Cell’intact enables to : Reduce the proinflammatory answer: reduction Interleukin-8 release reinforce the architectural epidermis network via the protection of tight junctions proteins (Claudine 1 and 4)

INCI name

Aqua (and) Polygonum Fagopyrum Seed Extract

Raw material

Buckwheat